April 11, 2022. The U.S. Food and Drug Administration (FDA) recently approved long-acting injectable cabotegravir and rilpivirine (Cabenuva) for use in children and adolescents aged ≥12 years and weighing ≥35 kg. This change has been incorporated in the Cabotegravir and Rilpivirine drug sections; other sections have not been updated yet. Figure 1-1. Algorithm for hospital decontamination of pediatric patients. Note: Children and their families (parents or caregivers) should not be separated unless critical medical issues take priority •Undresschild(by caregiverandhotzone personnel) •Placechildonstretcheror arestrainingdevice •Escortchildthroughthe decontaminationshower This guidance is intended to inform pediatric healthcare providers of up-to-date information about children with suspected or confirmed COVID-19 and about caring for children during the pandemic. Children are defined as age 1 month to 18 years for the purpose of this document. • In individuals ages 4 years and older with mild to moderate persistent asthma who are likely to be adherent to daily ICS treatment, the Expert Panel conditionally recommends against a short- term increase in the ICS dose for increased symptoms or decreased peak flow. Page 6 of 7 *Renal adjustment may be necessary. See Pediatric Antimicrobial Dosing Guidelines. 1Children who are not up-to-date for age with conjugate vaccines for S. pneumoniae or H. influenza type b 2Use amoxicillin-clavulanate ES (600 mg/42.9 mg/5 mL) to limit the risk of diarrhea associated with high doses of clavulanate 3Atypical pneumonia is characterized by slow progression of symptoms • There are approximately 20 million children aged <5 years in the United States; an additional approximately 4 million children aged 5 years have been eligible for the Pfizer-BioNTech vaccine for children aged 5-11 years since November 2021. • FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC) is Overview . The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delamanid in young children with multidrug- and rifampicin-resistant TB and decentralized these guidelines, which is a best-practice statement." Infectious Response Although adult sepsis guidelines recommend all patients begin antimicrobial therapy within one hour of recognizing sepsis, the pediatric guidelines recommend a two-phase process for assessing which children should receive immediate antibiotics. Those with septic shock Paediatric Clinical Guidelines 2022-24 From the inception of PiP, it was recognised that developing clinical guidelines together, was an efficient use of time and would assist PiP in meeting one of its objectives, "to improve the quality of services for children". Parenteral Nutrition Recommendations for Pediatric Patients (Calculated for normal organ function and normal caloric requirements) PN orders are due by 11 AM daily . JHH policy dictates that peripheral PN is limited to < 1000 mOsm/L. Central access is required for osmolarity ≥ 1000 mOsm/L. (Osmolarity is automatically calculated by EPIC.) Chapter 1: Normal Values in Children 1 Chapter 2: Childhood Immunisations 9 Chapter 3: Paediatric Fluid and Electrolyte Guidelines 24 Chapter 4: Developmental Milestones in Nor