Release of New Quality Improvement Organizations (QIO) Manual Chapter 5, “Quality of Care Review” by the Centers for Medicare and Medicaid Services (CMS) process pursuant to regulation (42 CFR 476.140) and QIO Manual Chapter revision (IOM 100-. 10 Chapter 5 – Quality of Care Review). The effective date of Release of New Quality Improvement Organizations (QIO) Manual Chapter 5, “Quality of Care Review” by the Centers for Medicare and Medicaid Services (CMS) Chapter IV - CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) Subchapter F - QUALITY IMPROVEMENT ORGANIZATIONS under both Part A and Part B.33 Quality Improvement Organizations (QIOs), 36 CMS, Transmittal 17: QIO Manual Chapter 5, “Quality of Care Review” (Apr. 6Quality Improvement Organization Manual Chapter 5 - Quality of Care Review Table Of Contents (Rev. 28, 10-21-16) Transmittals for Chapter 5 5000 (1) Has an ownership interest of 5 percent or more; other than a religious nonmedical institution as defined in § 440.170(b) of this chapter.