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what constitutes meaningful learning (in science) that must be strategically linked to the use of age-appropriate instructional interventions in order32 research-based instructional strategies include 1. Setting Objectives 2. Reinforcing Effort/Providing Recognition and 3. Cooperative Learning. There are do science more meaningfully: developmentally five phases in the 5Es Instructional model: Engaging, appropriate practices (DAP), 5Es instructional