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Define guideline. guideline synonyms, guideline pronunciation, guideline translation, English dictionary definition of guideline. n. A statement or other indication Guideline definition is - a line by which one is guided: such as. Definition of guideline in the Definitions.net dictionary. and translations of guideline in the most comprehensive dictionary definitions resource on the web.Definition of guideline: Recommended practice that allows some discretion or leeway in its interpretation, implementation, or use. guideline definition: 1. information intended to advise people on how something should be done or what something should be: 2. a piece of information that Definition of guideline - a general rule, principle, or piece of advice. Guideline definition, any guide or indication of a future course of action: guidelines on the government's future policy. See more. Guideline definition: If an organization issues guidelines on something, it issues official advice about how to | Meaning, pronunciation, translations and guideline meaning, definition, what is guideline: rules or instructions about the best way: Learn more. A guideline is a statement by which to determine a course of action. A guideline aims to streamline particular processes according to a set routine or sound practice. By definition, following a guideline is never mandatory. Guidelines are not binding and are not enforced.