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Quick Guide: DNA Shearing with ME220 Focused-ultrasonicator. Quick Guide. Application: DNA Shearing Protocols. Download PDF. Quick Guide: DNA Shearing with This Quick Guide provides DNA Shearing protocols when using microTUBE-15 and a Covaris S220 or E220. Focused-ultrasonicator. Please note that microTUBE-15 If you don't see the product insert or user manual you are looking for, please contact M220 Focused-ultrasonicator Setup & Instruction Manual.This Quick Guide provides DNA Shearing protocols when using microTUBE-130, microTUBE-50, microTUBE-15, microTUBE-500, or. miniTUBE and a Covaris M220 This Quick Guide provides recommendations for shearing single stranded Nucleic Acids (RNA, mRNA or ssDNA) with a. Covaris S-, E-, or LE-Series Focused- This Quick Guide provides DNA Shearing protocols when using microTUBE-130, microTUBE-50, microTUBE-15,. microTUBE-500, or miniTUBE and a Covaris E220 This Quick Guide provides DNA Shearing protocols when using microTUBE-130, microTUBE-50, microTUBE-15,. microTUBE-500, or miniTUBE and a Covaris S220 Focused- This Quick Guide provides DNA Shearing protocols when using microTUBE, microTUBE-50, microTUBE-15,. microTUBE-500, or miniTUBE and a Covaris LE220 This Quick Guide provides DNA Shearing protocols when using microTUBE or miniTUBE and a Covaris S2 or. E210 Focused-ultrasonicator. This Quick Guide provides recommendations for shearing single stranded Nucleic Acids (RNA, mRNA or ssDNA) with a. Covaris M-Series Focused-ultrasonicator.