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The 28th edition of this document provides updated tables for the CLSI AST standards M02, M07, and M11, and is available as a downloadable PDF or printed. PDF or printed document. M100 FREE. You can now quickly reference the most trusted AST breakpoints from anywhere with an Internet connection. CLSI supplement VET08. Wayne, PA: Clinical and Laboratory. Standards Institute; 2018. Table 2. MIC Breakpoints and Zone Diameter Breakpoints for Pseudomonascdc.gov/hicpac/pdf/isolation/isolation2007.pdf. Accessed November 3, 2011. 12. CLSI. Protection of Laboratory Workers From Occupationally Acquired Clinical and Laboratory Standards Institute (CLSI) (2018) Performance Standards for Antimicrobial Susceptibility Testing. CLSI Approved Standard M100-S15. The Clinical and Laboratory Standards Institute (CLSI) is a not-for-profit membership organization that brings together the varied perspectives and