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Administration Instructions. • There are two presentations of BYDUREON (i.e., a single dose tray and a single dose pen) [see. Before using BYDUREON BCise, read the full Instructions for Use that you received with your prescription and talk to your healthcare provider about how to Bydureon BCise pen • Alcohol swab • A clean, flat surface • Puncture-resistant container (see. “disposal” instructions at the end of these instructions).Store your pens in the refrigerator until you use them. You can keep a pen at room temperature for. 28 days. After that, throw it away. Get your pen ready:. Read these Instructions for Use before you start using BYDUREON Single-. Dose Tray and each time you get a refill. There may be new information. This.